Synthesis, In Vitro and in Cell Study of a New Spirooxindoles-Based N-Alkylated Maleimides Targeting HER2/3 Signaling Pathway

Author:

Barakat Assem1ORCID,Abu-Serie Marwa M.2,Ali M.1,Al-Majid Abdullah Mohammed1,Ashraf Sajda3,Zia Komal3,Ul-Haq Zaheer3ORCID,Al-Dhfyan Abdullah4,Abdel-Aziz Hatem A.5,El-Faham Ayman6,Domingo Luis R.7ORCID

Affiliation:

1. Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia

2. Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), New Borg El Arab, Egypt

3. Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

4. Stem Cell Therapy and Tissue Re-Engineering Program, King Faisal Specialized Hospital and Research Center, Riyadh, Saudi Arabia

5. Department of Applied Organic Chemistry, National Research Center, Giza, Egypt

6. Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, Egypt

7. Department of Organic Chemistry, University of Valencia, Valencia, Spain

Funder

Researchers Supporting Project

King Saud University, Riyadh, Saudi Arabia

Ministerio de Ciencias, Innovación y Universidades of the Spanish Government

Publisher

Informa UK Limited

Subject

Materials Chemistry,Organic Chemistry,Polymers and Plastics

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