1. Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy
2. Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy
3. Division of Anaesthesia, Analgesia, and Intensive Care, University of Perugia, Perugia, Italy
4. Unit of Internal Medicine, Terni University Hospital, Terni, Italy