Efficacy of emicizumab prophylaxis versus factor VIII prophylaxis for treatment of hemophilia A without inhibitors: network meta-analysis and sub-group analyses of the intra-patient comparison of the HAVEN 3 trial

Author:

Reyes Adriana1,Révil Cédric1,Niggli Markus1,Chebon Sammy1,Schlagmüller Simone2,Flacke Jan-Paul2,Zortel Max2,Paz-Priel Ido3,Asikanius Elina1,Hampton Roger1,Mahajan Anadi4,Schmidt Elvira5,Edwards Susan C.1

Affiliation:

1. F. Hoffmann-La Roche, Basel, Switzerland;

2. Roche Pharma AG, Grenzach-Wyhlen, Germany;

3. Genentech, San Francisco, CA, USA;

4. Bridge Medical, New Delhi, India;

5. Certara, Lörrach, Germany (formerly Analytica Laser)

Publisher

Informa UK Limited

Subject

General Medicine

Reference43 articles.

1. Centers for Disease Control and Prevention [Internet]. Data & statistics on hemophilia; 2018. Sep 6 [cited 2019 Mar]. Available from: https://www.cdc.gov/ncbddd/hemophilia/data.html.

2. National Heart, Lung, and Blood Institute [Internet]. Hemophilia: what is; 2013. [cited 2019 Mar]. Available from: www.nhlbi.nih.gov/health/health-topics/topics/hemophilia/.

3. A randomized clinical trial of prophylaxis in children with hemophilia A (the ESPRIT Study)

4. Quality of life in haemophilia A: Hemophilia Utilization Group Study Va (HUGS-Va)

5. Musculoskeletal Complications of Hemophilia

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