IL-27 overexpression alleviates inflammatory response in allergic asthma by inhibiting Th9 differentiation and regulating Th1/Th2 balance
Author:
Affiliation:
1. Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China
Funder
National Natural Science Foundation of China
Publisher
Informa UK Limited
Subject
Pharmacology,Toxicology,General Medicine,Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/08923973.2022.2077755
Reference25 articles.
1. IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells
2. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
3. IL-27 regulates the adherence, proliferation, and migration of MSCs and enhances their regulatory effects on Th1 and Th2 subset generations
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1. Mesenchymal stem cells alleviate inflammatory responses through regulation of T-cell subsets;European Journal of Pharmacology;2024-09
2. IL-27 Alleviates Airway Inflammation and Airway Hyperresponsiveness in Asthmatic Mice by Targeting the CD39/ATP Axis of Dendritic Cells;Inflammation;2023-12-20
3. The Differentially Expressed Genes Responsible for the Development of T Helper 9 Cells From T Helper 2 Cells in Various Disease States: Immuno-Interactomics Study;JMIR Bioinformatics and Biotechnology;2023-02-23
4. Interferon-γ Stimulates Interleukin-27 Derived from Dendritic Cells to Regulate Th9 Differentiation through STAT1/3 Pathway;Disease Markers;2022-10-18
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