Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells-Reference-Cited by-同舟云学术

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Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells

Published:2017-06-06 Issue:1 Volume:6 Page:1324730
ISSN:2001-3078
Container-title:Journal of Extracellular Vesicles
language:en
Short-container-title:Journal of Extracellular Vesicles

Author:

Zhu Xiaohua¹,Badawi Mohamed¹,Pomeroy Steven²,Sutaria Dhruvitkumar S.¹,Xie Zhiliang¹,Baek Alice¹,Jiang Jinmai²,Elgamal Ola A.¹,Mo Xiaokui³,Perle Krista La⁴,Chalmers Jeffrey⁵,Schmittgen Thomas D.²,Phelps Mitch A.¹

Affiliation:

1. College of Pharmacy, The Ohio State University, Columbus, OH, USA

2. College of Pharmacy, University of Florida, Gainesville, FL, USA

3. Department of Biostatistics, The Ohio State University, Columbus, OH, USA

4. College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA

5. College of Engineering, The Ohio State University, Columbus, OH, USA

Funder

National Center for Advancing Translational Sciences

Publisher

Wiley

Subject

Cell Biology,Histology

Link

https://www.tandfonline.com/doi/pdf/10.1080/20013078.2017.1324730

Reference55 articles.

1. Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

2. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

3. Functional MicroRNA Is Transferred between Glioma Cells

4. Isolation and Characterization of Exosomes from Cultures of Tissue Explants and Cell Lines

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