First-in-human clinical trial results with ABBV-184, a first-in-class T-cell receptor/anti-CD3 bispecific protein, in adults with previously treated AML or NSCLC

Author:

Peterlin Pierre1,Saada-Bouzid Esma2,Moskovitz Mor34,Pigneux Arnaud5,Yuda Junichiro6,Sinnollareddy Mahipal7,Henner William R.8,Chen Diana8,Freise Kevin J.7,Leibman Rachel S.8,Avigdor Abraham910,Shimizu Toshio1112

Affiliation:

1. Hematology Department, Nantes University Hospital, Nantes, France

2. Department of Medical Oncology, Cote d’Azur University, Centre Anticancer Antoine Lacassagne, Nice, France

3. Division of Oncology, Thoracic Cancer Service, Haifa, Israel

4. Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Israel

5. Department of Hematology, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France

6. Department of Hematology and Experimental Therapeutics, National Cancer Center Hospital East, Chiba, Japan

7. AbbVie Inc, North Chicago, IL, USA

8. AbbVie Inc, San Francisco, CA, USA

9. Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Ramat Gan, Israel

10. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

11. Department of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan

12. Department of Pulmonary Medicine and Medical Oncology, Wakayama Medical University Hospital, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan

Funder

Abbvie. ABBV-184 was developed

AbbVie. AbbVie funded this study

Publisher

Informa UK Limited

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