Design, synthesis and evaluation of novel norfloxacin analogs as potent anticancer and antioxidant agents

Author:

Qurban Faraz12ORCID,Shahzad Sohail Anjum3,Khaskheli Muhammad Saleh4,Khan Shafi ullah5,Khan Shujaat Ali1,Rauf Waqar6,Islam Shamsul1ORCID,Mannan Abdul1

Affiliation:

1. Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, 22060, Pakistan

2. Institute of Pharmaceutical Sciences, Peoples University of Medical & Health Sciences for Women, Nawabshah – Shaheed Benazirabad, Sindh, 67480, Pakistan

3. Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, 22060, Pakistan

4. Department of Anesthesiology, Peoples University of Medical & Health Sciences for Women, Nawab Shah – Shaheed Benazirabad, Sindh, 67480, Pakistan

5. Normandie University, UNICAEN, INSERM U1086 “ANTICIPE” (Interdisciplinary Research Unit for Cancers Prevention & Treatment), Centre François Baclesse, 3 avenue Général Harris, Caen, 14000, France

6. Pakistan Institute of Engineering & Applied Sciences, Health Biotechnology Division, National Institute for Biotechnology & Genetic Engineering (NIBGE-C, PIEAS), Faisalabad, 38000, Pakistan

Publisher

Informa UK Limited

Reference25 articles.

1. Mechanisms and Morphology of Cellular Injury, Adaptation, and Death

2. Congenital Diseases of DNA Replication: Clinical Phenotypes and Molecular Mechanisms

3. Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. (4th edition). New York: Garland Science; 2002. DNA Replication Mechanisms. Available from: https://www.ncbi.nlm.nih.gov/books/NBK26850/

4. Oxidative stress, inflammation, and cancer: How are they linked?

5. Cancer invasion and metastasis: molecular and cellular perspective. In Madame Curie Bioscience Database [Internet];Martin TA;Landes Bioscience.,2013

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