1. Department of Internal Medicine, University of Brescia and ASST Spedali Civili, Brescia, Italy
2. Department of Emergency, ASST Spedali Civili, Brescia, Italy
3. Department of Pharmacology, Faculty of Medicine, University Hospital Agostino Gemelli, Catholic University of the Sacred Heart, Rome, Italy
4. Department of Respiratory Medicine, Royal Brompton & Harefield NHS Trust, Harefield Hospital, Middlesex, UK