Gualou Guizhi decoction reverses brain damage with cerebral ischemic stroke, multi-component directed multi-target to screen calcium-overload inhibitors using combination of molecular docking and protein

Gualou Guizhi decoction reverses brain damage with cerebral ischemic stroke, multi-component directed multi-target to screen calcium-overload inhibitors using combination of molecular docking and protein–protein docking

Published:2017-11-29 Issue:1 Volume:33 Page:115-125
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Hu Juan¹²,Pang Wen-Sheng²³,Han Jing¹,Zhang Kuan³,Zhang Ji-Zhou¹,Chen Li-Dian¹²

Affiliation:

1. Fujian Academy of Traditional Chinese Medicine, Fuzhou, PR China;

2. School of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, PR China;

3. The Second People’s Hospital of Fujian Province, Fuzhou, PR China

Funder

Ministry of Science and Technology

Fujian Provincial Department of Science & Technology

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://tandfonline.com/doi/pdf/10.1080/14756366.2017.1396457

Reference26 articles.

1. Efficacious Naturally Occurring Anti-cerebral Ischaemia Extracts, Compounds and Formulations Data from Animal Models

2. Recommendations and treatment strategies for the management of acute ischemic stroke

3. Calcium channel blockers in cerebral ischaemia

4. Sphingomyelinase-induced ceramide production stimulate calcium-independent JNK and PP2A activation following cerebral ischemia

5. Traditional Chinese medicine in the Chinese health care system

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