Rational design, optimization, and biological evaluation of novel α-Phosphonopropionic acids as covalent inhibitors of Rab geranylgeranyl transferase-Reference-Cited by-同舟云学术

Rational design, optimization, and biological evaluation of novel α-Phosphonopropionic acids as covalent inhibitors of Rab geranylgeranyl transferase

Published:2022-03-30 Issue:1 Volume:37 Page:940-951
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Małolepsza Joanna¹^ORCID,Marchwicka Aleksandra²,Serwa Remigiusz A.³^ORCID,Niinivehmas Sanna P.⁴⁵^ORCID,Pentikäinen Olli T.⁴⁵^ORCID,Gendaszewska-Darmach Edyta²^ORCID,Błażewska Katarzyna M.¹^ORCID

Affiliation:

1. Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Łódź, Poland

2. Institute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Łódź, Poland

3. ReMedy International Research Agenda Unit, IMol Polish Academy of Sciences, Warsaw, Poland

4. Institute of Biomedicine, University of Turku, Turku, Finland

5. InFLAMES Research Flagship Center, University of Turku, Turku, Finland

Funder

the National Science Centre, Poland: Preludium

Sonata Bis

The Academy of Finland

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2022.2053525

Reference33 articles.

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4. Pfizer’s novel COVID-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study | Pfizer [Internet]. 2021 [cited 2021 Nov 6]. Available from: https://www.pfizer.com/news/press-release/press-release-detail/pfizers-novel-covid-19-oral-antiviral-treatment-candidate.

5. Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry

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