1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery-Reference-Cited by-同舟云学术

1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery

Published:2019-01-01 Issue:1 Volume:34 Page:1218-1225
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Raingeval Claire¹^ORCID,Cala Olivier¹^ORCID,Brion Béatrice¹,Le Borgne Marc²^ORCID,Hubbard Roderick Eliot³⁴^ORCID,Krimm Isabelle¹^ORCID

Affiliation:

1. Université de Lyon, CNRS, Université Claude Bernard Lyon 1, ENS Lyon, CRMN FRE 2034, Villeurbanne, France;

2. Université de Lyon, Université Claude Bernard Lyon 1, Faculté de Pharmacie – ISPB, EA 4446 Bioactive Molecules and Medicinal Chemistry, SFR Santé Lyon-Est CNRS UMS3453 – INSERM US7, Lyon, France;

3. YSBL, University of York, Heslington, York, UK;

4. Vernalis (R&D) Ltd, Granta Park, Abington, Cambridge, UK

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://tandfonline.com/doi/pdf/10.1080/14756366.2019.1636235

Reference34 articles.

1. Twenty years on: the impact of fragments on drug discovery

2. Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery

3. A three-stage biophysical screening cascade for fragment-based drug discovery

4. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

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