Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs)-Reference-Cited by-同舟云学术

Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs)

Published:2022-08-17 Issue:1 Volume:37 Page:2223-2240
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Riu Federico¹,Ibba Roberta¹,Zoroddu Stefano²,Sestito Simona³,Lai Michele⁴⁵,Piras Sandra¹,Sanna Luca²,Bordoni Valentina²,Bagella Luigi²⁶,Carta Antonio¹

Affiliation:

1. Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy

2. Department of Biomedical Sciences, University of Sassari, Sassari, Italy

3. Department of Chemical, Physical, Mathematical and Natural Sciences, University of Sassari, Sassari, Italy

4. Department of Translational Medicine and New Technologies in Medicine and Surgery, Retrovirus Centre, University of Pisa, Pisa, Italy

5. CISUP – Centre for Instrumentation Sharing – University of Pisa, Pisa, Italy

6. Center for Biotechnology, College of Science and Technology, Sbarro Institute for Cancer Research and Molecular Medicine, Temple University, Philadelphia, PA, USA

Funder

Regione Autonoma della Sardegna

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2022.2111680

Reference45 articles.

1. How to utilize academic research efforts in cancer drug discovery

2. Tubulin/Microtubules: Still a Promising Target for New Chemotherapeutic Agents

3. Anti-Microtubule Drugs