Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities

Author:

Chu Jung-Chun1,Tseng Hui-Ju23,Lee Sung-Bau1,Hsu Kai-Cheng1456,Hsin Ling-Wei7,Liang Ru-Hao2,Lin Tony Eight45,Gao Nain-Chu8,Chen Liang-Chieh3,Lu Wan-Hsun8,Wang Andrew H.-J9,Huang Wei-Jan128

Affiliation:

1. Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei, Taiwan

2. School of Pharmacy, Taipei Medical University, Taipei, Taiwan

3. Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California, United States

4. Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan

5. Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan

6. TMU Research Center for Drug Discovery, Taipei Medical University, Taipei, Taiwan

7. School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan

8. Graduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan

9. The Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan

Funder

Ministry of Science and Technology, Taiwan

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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