Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates-Reference-Cited by-同舟云学术

Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates

Published:2021-01-01 Issue:1 Volume:36 Page:437-449
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Lee Hyun Myung¹²^ORCID,Andrys Rudolf³^ORCID,Jonczyk Jakub⁴^ORCID,Kim Kyuneun¹²^ORCID,Vishakantegowda Avinash G.¹²^ORCID,Malinak David³^ORCID,Skarka Adam³^ORCID,Schmidt Monika³^ORCID,Vaskova Michaela³^ORCID,Latka Kamil⁴^ORCID,Bajda Marek⁴^ORCID,Jung Young-Sik¹²^ORCID,Malawska Barbara⁴^ORCID,Musilek Kamil³^ORCID

Affiliation:

1. Division of Bio and Drug Discovery, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea

2. Department of Medicinal Chemistry and Pharmacology, Daejeon, Republic of Korea

3. Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic

4. Department of Physicochemical Drug Analysis, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland

Funder

Ministry of Science and ICT of Korea

Ministry of Education, Youth and Sports of the Czech Republic

University of Hradec Kralove

The National Centre for Research and Development, Poland

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2020.1869954

Reference36 articles.

1. Novel Clinical Toxicology and Pharmacology of Organophosphorus Insecticide Self-Poisoning

2. Cholinesterases and the fine line between poison and remedy

3. Organophosphates⧸Nerve Agent Poisoning: Mechanism of Action, Diagnosis, Prophylaxis, And Treatment

4. Limitations and challenges in treatment of acute chemical warfare agent poisoning

5. Inhibition of cholinesterases with cationic phosphonyl oximes highlights distinctive properties of the charged pyridine groups of quaternary oxime reactivators

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