Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors

Author:

Gao Cheng-Zhi1,Dong Wei1,Cui Zhi-Wen1,Yuan Qiong1,Hu Xia-Min2,Wu Qing-Ming1,Han Xianlin3,Xu Yao4,Min Zhen-Li13

Affiliation:

1. Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, China;

2. College of Pharmacy, Shanghai University of Medicine & Health Sciences, Shanghai, China;

3. Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA;

4. College of Life Science and Health, Wuhan University of Science and Technology, Wuhan, China

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

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