Bromination of eudesmin isolated from araucaria araucana induces epimerization and give bromine derivatives with loss of anti-Candida activity

Author:

Bravo-Arrepol Gastón1,Becerra José1,Ortiz Leandro2,Cabrera-Pardo Jaime3ORCID,Schmidt Bernd4,Heydenreich Matthias4,Kelling Alexandra4,Sperlich Eric4,Karpiński Tomasz M.5,Paz Cristian6

Affiliation:

1. Laboratorio de Química de Productos Naturales, Departamento de Botánica, Facultad de Ciencias Naturales y Oceanográficas, Universidad de Concepción, Concepción, Chile

2. Instituto de Ciencias Químicas, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile

3. Laboratorio de Química Aplicada y Sustentable, Departamento de Química, Facultad de Ciencias, Universidad de Tarapacá, Arica, Chile

4. Institut für Chemie, Universität Potsdam, Potsdam, Germany

5. Chair and Department of Medical Microbiology, Poznań University of Medical Sciences, Poznań, Poland

6. Laboratory of Natural Products & Drug Discovery, Centre CEBIM, Universidad de La Frontera, Temuco, Chile

Funder

ANID of Chile government

Publisher

Informa UK Limited

Subject

Organic Chemistry,Plant Science,Biochemistry,Analytical Chemistry

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