<i>In silico</i> toxicologic profile and <i>in vivo</i> trypanocidal activity of estafietin, a sesquiterpene lactone isolated from Stevia alpina Griseb.-Reference-Cited by-同舟云学术

In silico toxicologic profile and in vivo trypanocidal activity of estafietin, a sesquiterpene lactone isolated from Stevia alpina Griseb.

Published:2023-03-20 Issue:4 Volume:38 Page:690-695
ISSN:1478-6419
Container-title:Natural Product Research
language:en
Short-container-title:Natural Product Research

Author:

Elso Orlando G.¹²,Cerny Natacha³⁴,Laurella Laura C.¹²,Bivona Augusto E.⁴⁵,Sánchez Alberti Andrés³⁵,Morales Celina⁶,Catalán Cesar A. N.⁷,Malchiodi Emilio L.⁴⁵^ORCID,Sülsen Valeria P.¹²^ORCID

Affiliation:

1. Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, 2nd floor, (C1113AAD), Buenos Aires, Argentina

2. Instituto de Química y Metabolismo del Fármaco (IQUIMEFA), CONICET – Universidad de Buenos Aires, Junín 956, 2nd floor, (C1113AAD), Buenos Aires, Argentina

3. Instituto de Microbiología y Parasitología Médica (IMPaM), CONICET – Universidad de Buenos Aires, Paraguay 2155, 13th floor, (C1121ABG), Buenos Aires, Argentina

4. Instituto de Estudios de la Inmunidad Humoral (IDEHU), CONICET – Universidad de Buenos Aires, Junín 956, 4th floor, (C1113AAD), Buenos Aires, Argentina

5. Cátedra de Inmunología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, 4th floor, (C1113AAD), Buenos Aires, Argentina

6. Departamento de Patología, Facultad de Medicina, Instituto de Fisiopatología Cardiovascular, Universidad de Buenos Aires, Paraguay 2155 (C1121ABG), Buenos Aires, Argentina

7. Instituto de Química Orgánica, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 471, (T4000INI), San Miguel de Tucumán, Tucumán, Argentina

Funder

National Scientific and Technical Research Council

University of Buenos Aires

Publisher

Informa UK Limited

Subject

Organic Chemistry,Plant Science,Biochemistry,Analytical Chemistry

Link

https://www.tandfonline.com/doi/pdf/10.1080/14786419.2023.2188208

Reference23 articles.

1. Impairment in Natural Killer Cells Editing of Immature Dendritic Cells by Infection with a Virulent Trypanosoma cruzi Population

2. Antiplasmodial Activity

3. Efficacy of Lychnopholide Polymeric Nanocapsules after Oral and Intravenous Administration in Murine Experimental Chagas Disease

4. Trypanocidal Activity of Four Sesquiterpene Lactones Isolated from Asteraceae Species

5. Mode of action of the sesquiterpene lactones eupatoriopicrin and estafietin on Trypanosoma cruzi