Protease propeptide structures, mechanisms of activation, and functions
Author:
Affiliation:
1. Rega Institute for Medical Research, Department of Microbiology, Immunology and Transplantation, Laboratory of Immunobiology, KU Leuven, Leuven, Belgium
Publisher
Informa UK Limited
Subject
Molecular Biology,Biochemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/10409238.2020.1742090
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1. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
2. Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis
3. ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis, and increased tumor growth
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