Durvalumab in cancer medicine: a comprehensive review

Author:

Alvarez-Argote Juliana1,Dasanu Constantin A.23

Affiliation:

1. Department of Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI, USA

2. Department of Hematology-Oncology, Eisenhower Lucy Curci Cancer Center, Rancho Mirage, CA, USA

3. Department of Hematology-Oncology, University of California San Diego Health System, San Diego, CA, USA

Funder

not funded

Publisher

Informa UK Limited

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology

Reference38 articles.

1. Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab

2. Identification and Characterization of MEDI4736, an Antagonistic Anti–PD-L1 Monoclonal Antibody

3. Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab

4. U.S. Food and Drug Administration. Highlights of prescribing information. Imfinzi™ (durvalumab) injection, for intravenous use. 2017 [cited 2018]; Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/761069s000lbl.pdf

5. U.S. Food and Drug Administration. FDA Summary of Safety and Effectiveness Data. (SSED). 2017 In vitro diagnostic immunohistochemistry (IHC) for detection of PD-L1 protein in formalin-fixed, paraffin-embedded (FFPE) human tissue sections. [cited 2018 Nov 23] Available from: https://www.accessdata.fda.gov/cdrh_docs/pdf16/P160046B.pdf

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