Trastuzumab deruxtecan in HER2-positive metastatic breast cancer and beyond

Author:

Perez Jose12,Garrigós Laia1,Gion Maria34,Jänne Pasi A.5,Shitara Kohei6,Siena Salvatore78,Cortés Javier129

Affiliation:

1. International Breast Cancer Center, Quiron Group, Barcelona, Spain

2. Medical Department, Medica Scientia Innovation Research (MedSIR), Valencia, Spain

3. Quironsalud Group, Madrid, Spain

4. Department of Medical Oncology, Hospital Universitario Ramón Y Cajal, Madrid, Spain

5. Department of Medical Oncology, Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA

6. Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan

7. Department of Oncology and Hematology-Oncology, Università Degli Studi Di Milano, Milan, Italy

8. Niguarda Cancer Center Grande Ospedale Metropolitano Niguarda, Milan, Italy

9. Department of Medical Oncology, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain

Funder

This paper is funded by Daiichi Sankyo.

Publisher

Informa UK Limited

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology

Reference77 articles.

1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

2. 4th ESO–ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 4)

3. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology (NCCN Guidelines): breast cancer. (Version 6.2020). 2020 Sept 8. [cited November 18, 2020] Available from: https://www.nccn.org/professionals/physician_gls/pdf/breast.pdf

4. EGFR/HER2 in breast cancer: a biological approach for molecular diagnosis and therapy

5. The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis

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