Emerging role for the Serum Response Factor (SRF) as a potential therapeutic target in cancer
Author:
Affiliation:
1. Cancer Biology and Therapeutics Laboratory, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland
2. UCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin, Ireland
Funder
OPTi-PREDICT
Strategic Research Programme Precision Oncology Ireland
Erasmus Plus Programme
Publisher
Informa UK Limited
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/14728222.2022.2032652
Reference115 articles.
1. Serum response factor: toggling between disparate programs of gene expression
2. Serum response factor: master regulator of the actin cytoskeleton and contractile apparatus
3. SRF Co-factors Control the Balance between Cell Proliferation and Contractility
4. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
5. Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors
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