Combination of PD-1 Checkpoint Blockade and Botulinum Toxin Type A1 Improves Antitumor Responses in Mouse Tumor Models of Melanoma and Colon Carcinoma-Reference-Cited by-同舟云学术

Combination of PD-1 Checkpoint Blockade and Botulinum Toxin Type A1 Improves Antitumor Responses in Mouse Tumor Models of Melanoma and Colon Carcinoma

Published:2023-07-05 Issue:6 Volume:52 Page:749-766
ISSN:0882-0139
Container-title:Immunological Investigations
language:en
Short-container-title:Immunological Investigations

Author:

Kwak Seongsung¹²^ORCID,Lee Ji-Young²^ORCID,Kim Min Ju¹,Lee Hyo Jin¹,Lee Dong-Kyu¹,Kang Jiyeon²,Kang Won-ho³^ORCID,Son Woo-Chan⁴^ORCID,Cruz Deu John M.¹^ORCID

Affiliation:

1. Pharmacology and Toxicology Department, Medytox Gwanggyo R&D Center, Yeongtong-gu, Suwon-si, Republic of Korea

2. Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

3. Medytox Korea Co. Ltd., Medytox Gwanggyo R&D Center, Yeongtong-gu, Suwon-si, Republic of Korea

4. Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

Funder

supported

Publisher

Informa UK Limited

Subject

General Medicine,Immunology

Link

https://www.tandfonline.com/doi/pdf/10.1080/08820139.2023.2232403

Reference60 articles.

1. Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade

2. Prevention of pancreatic cancer by the beta-blocker propranolol

3. Mechanisms of cancer dissemination along nerves

4. Botulinum toxin potentiates cancer radiotherapy and chemotherapy.

5. Use of botulinum toxins in cancer therapy

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