Mathematical Modelling of the Primary and Secondary Drying Stages of Bulk Solution Freeze-Drying in Trays: Parameter Estimation and Model Discrimination by Comparison of Theoretical Results With Experimental Data
Author:
Affiliation:
1. a Department of Chemical Engineering and Biochemical Processing Institute University of Missouri-Rolla , Rolla, Missouri, 65409-1230, U.S.A.
Publisher
Informa UK Limited
Subject
Physical and Theoretical Chemistry,General Chemical Engineering
Link
https://www.tandfonline.com/doi/pdf/10.1080/07373939708917262
Reference16 articles.
1. A theory for the primary and secondary drying stages of the freeze-drying of pharmaceutical crystalline and amorphous solutes: comparison between experimental data and theory
2. Freeze-Drying of Pharmaceutical Crystalline and Amorphous Solutes in Vials: Dynamic Multi-Dimensional Models of the Primary and Secondary Drying Stages and Qualitative Features of the Moving Interface
3. Research and Development Needs and Opportunities in Freeze Drying
4. An analysis of the lyophilization process using a sorption-sublimation model and various operational policies
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