Vaccination inducing durable and robust antigen-specific Th1/Th17 immune responses contributes to prophylactic protection against Mycobacterium avium infection but is ineffective as an adjunct to antibiotic treatment in chronic disease

Author:

Lee Ju Mi1ORCID,Park Jiyun1ORCID,Reed Steven G2ORCID,Coler Rhea N345ORCID,Hong Jung Joo6ORCID,Kim Lee-Han1ORCID,Lee Wonsik7,Kwon Kee Woong1ORCID,Shin Sung Jae1ORCID

Affiliation:

1. Department of Microbiology, Institute for Immunology and Immunological Disease, Graduate School of Medical science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, South Korea

2. HDT Bio Corp, Seattle, WA, USA

3. Seattle Children’s Research Institute, Center for Global Infectious Disease Research, Seattle, WA, USA

4. Department of Global Health, University of Washington, Seattle, WA, USA

5. Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA

6. National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, South Korea

7. School of Pharmacy, Sungkyunkwan University, Suwon, South Korea

Funder

National Research Foundation of Korea

Korea Research Institute of Bioscience and Biotechnology

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),Immunology,Microbiology,Parasitology

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