Modeling pediatric AML FLT3 mutations using CRISPR/Cas12a- mediated gene editing
Author:
Affiliation:
1. Gene Editing Institute, Helen F Graham Cancer Center & Research Institute, Newark, DE, USA
2. Department of Medical and Molecular Sciences, University of Delaware, Willard E. Hall Education Building, Newark, DE, USA
Funder
National Institute of General Medical Sciences
The Nemours/B + Foundation
LSM880 confocal microscope: Microscopy equipment
NIH-NIGMS
NSF
the State of Delaware
State of Delaware
CTCR Flow Cytometry Core Facility
Publisher
Informa UK Limited
Subject
Cancer Research,Oncology,Hematology
Link
https://www.tandfonline.com/doi/pdf/10.1080/10428194.2020.1805740
Reference53 articles.
1. RNA-Guided Human Genome Engineering via Cas9
2. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
3. Recent advances in genome editing of stem cells for drug discovery and therapeutic application
4. Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains
5. CRISPR–Cas: a tool for cancer research and therapeutics
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1. Advances in CRISPR-Cas systems for blood cancer;Progress in Molecular Biology and Translational Science;2024
2. Utilization of CRISPR-Mediated Tools for Studying Functional Genomics in Hematological Malignancies: An Overview on the Current Perspectives, Challenges, and Clinical Implications;Frontiers in Genetics;2022-01-28
3. A toolmaker’s perspective on CRISPR-directed gene editing as a therapeutic strategy for leukemia and beyond;Expert Review of Hematology;2021-06-07
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