1. Central Unit Biostatistics German Cancer research Center (DKFZ), P.O. Box 101949, D-69009 Heidelberg, Germany
2. Department Technical Security GSF-National Research Center for Environment and Health, Ingolstädter Landstr.1, D-85764 Neuherberg, Germany
3. Institute of Toxicology, GSF-National Research Center for Environment and Health, Ingolstädter Landstr.1, D-85764 Neuherberg, Germany
4. Product Safety-Regulations, Toxicology and Ecology, BASF AG, D-67056 Ludwigshafen/Rhein, Germany
5. Toxicology-Rodent Studies and Genetic Toxicology, Bayer AG, D-42096 Wuppertal, Germany
6. Department of Cellular and Molecular Pathology, German Cancer Research Center (DKFZ), P.O. Box 101949, D-69009 Heidelberg, Germany
7. Department of Toxicology, Institute of Pharmacology and Toxicology, University of Tübingen, Wilhelmstrasse 56, D-72074 Tübingen, Germany
8. Central Unit Biostatistics German Cancer research Center (DKFZ), P.O. Box 101949, D-69009 Heidelberg, Germany,