Quantifying Efficiency Gains of Innovative Designs of Two-Arm Vaccine Trials for COVID-19 Using an Epidemic Simulation Model
Author:
Affiliation:
1. Imperial College London, Department of Infectious Disease Epidemiology, London, UK;
2. MRC Biostatistics Unit, University of Cambridge, Cambridge, UK
Funder
Department of Health and Social Care
NIHR
U.K. Medical Research Council programme
UK Medical Research Council programme
Publisher
Informa UK Limited
Subject
Pharmaceutical Science,Statistics and Probability
Link
https://www.tandfonline.com/doi/pdf/10.1080/19466315.2021.1939774
Reference44 articles.
1. Performance of different clinical trial designs to evaluate treatments during an epidemic
2. Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: A living systematic review and meta-analysis
3. Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs
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