Bayesian Hierarchical Modeling and Biomarker Cutoff Identification in Basket Trials
Author:
Affiliation:
1. Department of Statistics and Actuarial Science, The University of Hong Kong, Pokfulam Road, Hong Kong;
2. Ono Pharmaceutical Co., Ltd., Osaka, Japan
Publisher
Informa UK Limited
Subject
Pharmaceutical Science,Statistics and Probability
Link
https://www.tandfonline.com/doi/pdf/10.1080/19466315.2020.1811146
Reference38 articles.
1. Platform Trial Designs in Drug Development
2. Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review
3. Adaptive Design for a Confirmatory Basket Trial in Multiple Tumor Types Based on a Putative Predictive Biomarker
4. Bayesian hierarchical modeling of patient subpopulations: Efficient designs of Phase II oncology clinical trials
5. A Bayesian method to estimate the optimal threshold of a marker used to select patients' treatment
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