Development of an enhanced formulation to minimize pharmacokinetic variabilities of a weakly basic drug compound-Reference-Cited by-同舟云学术

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Development of an enhanced formulation to minimize pharmacokinetic variabilities of a weakly basic drug compound

Published:2022-04-21 Issue:4 Volume:27 Page:406-413
ISSN:1083-7450
Container-title:Pharmaceutical Development and Technology
language:en
Short-container-title:Pharmaceutical Development and Technology

Author:

Pu Yu (Elaine)¹,Menger Robert²,Tong Zeen³,Gaebele Tracy⁴

Affiliation:

1. Oral Product Development, Global Pharmaceutical Sciences, Bristol-Myers Squibb, Summit, NJ, USA

2. Analytical Chemistry, Chemical Process Development, Bristol-Myers Squibb, Summit, NJ, USA

3. Drug Metabolism and Pharmacokinetics, Nonclinical Disposition Assessment, Bristol-Myers Squibb, Summit, NJ, USA

4. Material Science and Engineering, Global Pharmaceutical Sciences, Bristol-Myers Squibb, Summit, NJ, USA

Publisher

Informa UK Limited

Subject

Pharmaceutical Science,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/10837450.2022.2070206

Reference25 articles.

1. Studies on Solubility Enhancement of Poorly Soluble NSAID Using Dual Approach of Micro-environmental pH Modulation and Melt Granulation

2. Improved dissolution and absorption of ketoconazole in the presence of organic acids as pH-modifiers

3. Enhanced pharmacokinetic performance of dapoxetine hydrochloride via the formulation of instantly-dissolving buccal films with acidic pH modifier and hydrophilic cyclodextrin: Factorial analysis, in vitro and in vivo assessment

4. Microenvironmental pH Modulation in Solid Dosage Forms

5. Formulation of Solid Dosage Forms to Overcome Gastric pH Interaction of the Factor Xa Inhibitor, BMS-561389

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1. Review of industrially recognized polymers and manufacturing processes for amorphous solid dispersion based formulations;Pharmaceutical Development and Technology;2023-07-14

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