Formulation and stability study of hydroxychloroquine sulfate oral suspensions

Author:

El Mershati Sarah1,Thouvenin Agathe1ORCID,Secretan Philippe-Henri1,De Lonlay Pascale23,Tuchmann-Durand Caroline4,Cisternino Salvatore15,Schlatter Joël1

Affiliation:

1. Department of Pharmacy, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France

2. Reference Center for Inherited Metabolic Diseases, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France

3. INSERM, Paris, France

4. Imagine Institut des Maladies Génétiques, Paris, France and Department of Biotherapy, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France

5. Faculté de Pharmacie, Université de Paris, Paris, France

Publisher

Informa UK Limited

Subject

Pharmaceutical Science,General Medicine

Reference26 articles.

1. New use for an old treatment: Hydroxychloroquine as a potential treatment for systemic vasculitis

2. EMA: Annex to the European Commission guideline on ‘Excipients in the labelling and package leaflet of medicinal products for human use’ (SANTE-2017-11668): European Medicines Agency; [accessed 2020 Aug 07]. https://www.ema.europa.eu/en/documents/scientific-guideline/annex-european-commission-guideline-excipients-labelling-package-leaflet-medicinal-products-human_en.pdf.

3. EMA: ICH Topic Q1A(R2): stability testing of new drug substances and products: European Medicines Agency; [accessed 2020 Aug 07]. https://www.ema.europa.eu/en/documents/scientific-guideline/ich-q-1-r2-stability-testing-new-drug-substances-products-step-5_en.pdf.

4. Hydroxychloroquine Reverses Platelet Activation Induced by Human IgG Antiphospholipid Antibodies

5. European Pharmacopoeia 8.0. 2013. Efficacy of antimicrobial preservation 01/2011:50103. EDQM Council of Europe 8th edition, Strasbourg, France, 600–601.

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