Drug discovery for DNA break repair system by screening from TCM database and molecular dynamics approach

Author:

Chang Tung-Ti1,Sun Mao-Feng2,Chen Kuan-Chung3,Wong Yung-Hao3,Yang Shun-Chieh3,Chen Hsin-Yi3,Tsai Fuu-Jen45,Fisher Mark6,Lee Chun-Lin7,Fang Wen-Chang7,Chen Calvin Yu-Chian3468

Affiliation:

1. a Department of Chinese Pediatrics , China Medical University Hospital , Taichung, Taiwan ROC

2. b Department of Acupuncture , China Medical University Hospital , Taichung, Taiwan ROC

3. c Laboratory of Computational and Systems Biology , School of Chinese Medicine, China Medical University , Taichung, 40402, Taiwan ROC

4. d Department of Bioinformatics , Asia University , Taichung, 41354, Taiwan ROC

5. e Department of Medical Genetics, Pediatrics and Medical Research , College of Chinese Medicine, China Medical University , Taichung, 40402, Taiwan ROC

6. f Harvard-MIT Division of Health Sciences and Technology , 77 Massachusetts Avenue, Cambridge, MA, 02139, USA

7. g Department of Business Administration , National Taipei University , Taipei, Taiwan ROC

8. h Computational and Systems Biology , Massachusetts Institute of Technology , Cambridge, MA, 02139, USA

Publisher

Informa UK Limited

Subject

Condensed Matter Physics,General Materials Science,General Chemical Engineering,Modeling and Simulation,Information Systems,General Chemistry

Reference29 articles.

1. Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining

2. Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

3. A. Rivera-Calzada, L. Spagnolo, L.H. Pearl, and O. Llorca, Structural model of full-length human Ku70–Ku80 heterodimer and its recognition of DNA and DNA-PKcs, EMBO Rep. 8 (2007), pp. 56–62

4. Ku is associated with the telomere in mammals

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3