A method of gene expression data transfer from cell lines to cancer patients for machine-learning prediction of drug efficiency

Author:

Borisov Nicolas12ORCID,Tkachev Victor23,Suntsova Maria245,Kovalchuk Olga67,Zhavoronkov Alex8,Muchnik Ilya9,Buzdin Anton12345ORCID

Affiliation:

1. National Research Centre “Kurchatov Institute”, Centre for Convergence of Nano-, Bio-, Information and Cognitive Sciences and Technologies, Moscow, Russia

2. Department of R&D, First Oncology Research and Advisory Center, Moscow, Russia

3. Department of R&D, OmicsWay Corporation, Walnut, CA, USA

4. Group for Genomic Regulation of Cell Signaling Systems, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia

5. Laboratory of Bioinformatics, D. Rogachyov Federal Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, 117198, Russia

6. Department of Biological Sciences, University of Lethbridge, Lethbridge, AB, Canada

7. Canada Cancer and Aging Research Laboratories, Lethbridge, AB, Canada

8. Insilico Medicine, Inc, ETC, Johns Hopkins University, Baltimore, MD, USA

9. Rutgers University, Hill Center, Busch Campus, Piscataway, NJ, USA

Funder

National Research Center "Kurchatov Institute"

Publisher

Informa UK Limited

Subject

Cell Biology,Developmental Biology,Molecular Biology

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