In vivo trafficking of a tumor-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart-Reference-Cited by-同舟云学术

In vivo trafficking of a tumor-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart

Published:2021-01-01 Issue:1 Volume:10 Page:
ISSN:2162-402X
Container-title:OncoImmunology
language:en
Short-container-title:OncoImmunology

Author:

Man Francis¹²^ORCID,Koers Alexander¹,Karagiannis Panagiotis³^ORCID,Josephs Debra H.³⁴^ORCID,Bax Heather J.³⁴^ORCID,Gilbert Amy E.³,Dodev Tihomir S.⁴⁵⁶,Mele Silvia³^ORCID,Chiaruttini Giulia³^ORCID,Crescioli Silvia³^ORCID,Chauhan Jitesh³⁴,Blower Julia E.¹,Cooper Margaret S.¹,Spicer James⁴⁷^ORCID,Karagiannis Sophia N.³⁸^ORCID,Blower Philip J.¹^ORCID

Affiliation:

1. School of Biomedical Engineering & Imaging Sciences, King’s College London, London, UK

2. School of Cancer & Pharmaceutical Sciences, Institute of Pharmaceutical Science, King’s College London, London, UK

3. School of Basic & Medical Biosciences, St John’s Institute of Dermatology, King’s College London, London, UK

4. School of Cancer & Pharmaceutical Sciences, Guy’s Hospital, King’s College London, London, UK

5. School of Basic and Medical Biosciences, Randall Centre for Cell and Molecular Biophysics, King’s College London, London, UK

6. Allergic Mechanisms in Asthma, Asthma UK Centre, King’s College London, London, UK

7. Cancer Centre at Guy’s, Guy’s and St Thomas’ NHS Foundation Trust, London, UK

8. School of Cancer & Pharmaceutical Sciences, Breast Cancer Now Research Unit, King’s College London, Guy’s Hospital, London, UK

Funder

Wellcome EPSRC Centre for Medical Engineering at KCL

Comprehensive Cancer Imaging Centre funded by CRUK and EPSRC

Medical Research Council Confidence in Concepts scheme

CRUK/NIHR in England/DoH for Scotland, Wales and Northern Ireland Experimental Cancer Medicine Centre

Cancer Research UK King’s Health Partners Centre at King’s College London

Cancer Research UK

Academy of Medical Sciences

Guy’s and St Thomas’s Foundation Trust Charity Melanoma Special Fund

Medical Research Council

Breast Cancer Now

(NIHR) Biomedical Research Centre based at Guy’s and St Thomas’ NHS Foundation Trust and KCL

Research England

CRUK City of London Centre

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2021.1966970

Reference62 articles.

1. The state-of-play and future of antibody therapeutics

2. The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

3. Building better monoclonal antibody-based therapeutics

4. The Structural Basis of Antibody-Antigen Recognition

5. IgE Antibodies: From Structure to Function and Clinical Translation

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