Mice transgenic for human<i>CTLA4-CD28</i>fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells-Reference-Cited by-同舟云学术

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Mice transgenic for humanCTLA4-CD28fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells

Published:2022-01-04 Issue:1 Volume:11 Page:
ISSN:2162-402X
Container-title:OncoImmunology
language:en
Short-container-title:OncoImmunology

Author:

Lee Gyu Jin¹²,Jun Yukyung³⁴,Jeon Yoon Kyung⁵⁶,Lee Daekee¹,Lee Sanghyuk¹²³,Kim Jaesang¹²³

Affiliation:

1. Department of Life Science, Ewha Womans University, Seoul, Korea

2. Ewha Research Center for Systems Biology, Seoul, Korea

3. Ewha-JAX Cancer Immunotherapy Research Center, Seoul, Korea

4. Center for Supercomputing Applications, Division of National Supercomputing, Korea Institute of Science and Technology Information, Daejeon, Korea

5. Department of Pathology, Seoul National University College of Medicine, Seoul, Korea

6. fCancer Research Institute, Seoul National University, Seoul, Korea

Funder

National Research Foundation of Korea

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2021.2015170

Reference40 articles.

1. CD28 and CTLA-4 coreceptor expression and signal transduction

2. Differential T Cell Costimulatory Requirements in CD28-Deficient Mice

3. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

4. Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4

5. Frequent CTLA4-CD28 gene fusion in diverse types of T-cell lymphoma

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