ADA/CD26 axis increases intra-tumor PD-1 + CD28 + CD8 + T-cell fitness and affects NSCLC prognosis and response to ICB-Reference-Cited by-同舟云学术

ADA/CD26 axis increases intra-tumor PD-1 ⁺ CD28 ⁺ CD8 ⁺ T-cell fitness and affects NSCLC prognosis and response to ICB

Published:2024-06-21 Issue:1 Volume:13 Page:
ISSN:2162-402X
Container-title:OncoImmunology
language:en
Short-container-title:OncoImmunology

Author:

Franzese Ornella¹,Palermo Belinda²,Frisullo Giuseppe²,Panetta Mariangela²,Campo Giulia²,D’Andrea Daniel³,Sperduti Isabella⁴,Taje Riccardo⁵,Visca Paolo⁶,Nisticò Paola²^ORCID

Affiliation:

1. Department of Systems Medicine, University of Rome ”Tor Vergata”, Rome, Italy

2. Tumor Immunology and Immunotherapy Unit, IRCCS-Regina Elena National Cancer Institute, Rome, Italy

3. Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham, UK

4. Biostatistics and Scientific Direction, IRCCS-Regina Elena National Cancer Institute, Rome, Italy

5. Thoracic-Surgery Unit, IRCCS-Regina Elena National Cancer Institute, Rome, Italy

6. Pathological Anatomy Unit, IRCCS-Regina Elena National Cancer Institute, Rome, Italy

Funder

supported by Associazione Italiana Ricerca s

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2024.2371051

Reference26 articles.

1. CD28/PD1 co-expression: dual impact on CD8+ T cells in peripheral blood and tumor tissue, and its significance in NSCLC patients' survival and ICB response

2. Cut to the chase: a review of CD26/dipeptidyl peptidase-4's (DPP4) entanglement in the immune system

3. Potential clinical implications of CD4+CD26high T cells for nivolumab treated melanoma patients

4. Moonlighting Adenosine Deaminase: A Target Protein for Drug Development

5. Characterization of adenosine deaminase binding to human CD26 on T cells and its biologic role in immune response.