Safety, immunogenicity, and lot-to-lot consistency of a split-virion quadrivalent influenza vaccine in younger and older adults: A phase III randomized, double-blind clinical trial

Author:

Sesay Sanie1,Brzostek Jerzy2,Meyer Ingo3,Donazzolo Yves4,Leroux-Roels Geert5,Rouzier Régine6,Astruc Béatrice7,Szymanski Henryk8,Toursarkissian Nicole9,Vandermeulen Corinne10,Kowalska Edyta11,Van Damme Pierre12,Salamand Camille1,Pepin Stephanie1

Affiliation:

1. Sanofi Pasteur, Marcy l'Etoile, France

2. Clinic of Infectious Diseases Health Care Team, Dębica, Poland

3. CRS Clinical Research Services Kiel GmbH, Lübeck, Germany

4. Eurofins-Optimed, Gières, France

5. Center for Vaccinology, Ghent University and University Hospital, Gent, Belgium

6. Centre CAP, Centre Médical Odysseum, Montpellier, France

7. Biotrial, Rennes Cedex, France

8. St Hedwig of Silesia Hospital, Department of Paediatrics, Prusicka, Trzebnica, Poland

9. Medic Trials, Berlin, Germany

10. Leuven University Vaccinology Center, Leuven, Belgium

11. “Medyk”, Wola, Poland

12. Centre for the Evaluation of Vaccination, Vaccine & Infectious Disease Institute, Antwerpen (Wilrijk), Belgium

Publisher

Informa UK Limited

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference33 articles.

1. Multiple Genotypes of Influenza B Virus Circulated between 1979 and 2003

2. Cocirculation of two distinct evolutionary lineages of influenza type B virus since 1983

3. National Advisory Committee on Immunization (NACI). Statement on seasonal influenza vaccine for 2014–2015. Ottawa, Canada: Public Health Agency of Canada;2014 [accessed 2016 Aug 29]. http://www.phac-aspc.gc.ca/naci-ccni/flu-grippe-eng.php.

4. The rationale for quadrivalent influenza vaccines

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