Mechanism of resistance to acyclovir in thymidine kinase mutants from Herpes simplex virus type 1: a computational approach-Reference-Cited by-同舟云学术

Mechanism of resistance to acyclovir in thymidine kinase mutants from Herpes simplex virus type 1: a computational approach

Published:2019-06-13 Issue:7 Volume:38 Page:2116-2127
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Rabelo Vitor Won-Held¹,Romeiro Nelilma Correia²,Paixão Izabel Christina Nunes de Palmer¹,Abreu Paula Alvarez³^ORCID

Affiliation:

1. Programa de Pós-graduação em Ciências e Biotecnologia, Instituto de Biologia, Universidade Federal Fluminense - Campus do Valonguinho, Niterói, Brazil;

2. Laboratório Integrado de Computação Científica, Universidade Federal do Rio de Janeiro - Campus Macaé, Brazil;

3. Instituto de Biodiversidade e Sustentabilidade, Universidade Federal do Rio de Janeiro, Macaé, Brazil

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2019.1625443

Reference57 articles.

1. Structure to 1.9 Å resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir

2. The Protein Data Bank

3. HSV antivirals – current and future treatment options

4. Effect on substrate binding of an alteration at the conserved aspartic acid-162 in herpes simplex virus type 1 thymidine kinase

5. A Method to Identify Protein Sequences That Fold into a Known Three-Dimensional Structure

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