Experiment and molecular dynamics simulations reveal proanthocyanidin B2 and B3 can inhibit prion aggregation by different mechanisms
Author:
Affiliation:
1. Faculty of Applied Sciences, Macao Polytechnic University, Macao, SAR, China
2. College of Chemical Engineering, Shijiazhuang University, Shijiazhuang, China
3. School of Pharmacy, Lanzhou University, Lanzhou, China
Funder
Macao Polytechnic University
Publisher
Informa UK Limited
Subject
Molecular Biology,General Medicine,Structural Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/07391102.2023.2209663
Reference45 articles.
1. Recent developments in the pathogenesis, diagnosis, and therapy of prion diseases
2. Prions: Protein Aggregation and Infectious Diseases
3. Essential dynamics of proteins
4. Crystal structure of human prion protein bound to a therapeutic antibody
5. Influence of fullerenol on hIAPP aggregation: amyloid inhibition and mechanistic aspects
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