Evaluation of the changes in exposure to thiol compounds in chronic kidney disease patients using the PBPK model-Reference-Cited by-同舟云学术

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Evaluation of the changes in exposure to thiol compounds in chronic kidney disease patients using the PBPK model

Published:2020-08-12 Issue:1 Volume:51 Page:31-39
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Takubo Hiroaki¹,Taniguchi Toshio¹,Iwanaga Kazunori²,Nomura Yukihiro¹

Affiliation:

1. Drug Metabolism and Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., Osaka, Japan

2. Education and Research Center for Clinical Pharmacy, Osaka University of Pharmaceutical Sciences, Osaka, Japan

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2020.1805816

Reference38 articles.

1. Interaction of the active metabolite of prasugrel, R-138727, with cysteine 97 and cysteine 175 of the human P2Y12receptor

2. Targeted Covalent Inhibitors for Drug Design

3. Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies

4. Can N-acetylcysteine reverse the antiplatelet effects of clopidogrel? An in vivo and vitro study

5. Pharmacokinetics of intravenous 2-mercaptopropionylglycine in man

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Application of a physiologically based pharmacokinetic model in predicting captopril disposition in children with chronic kidney disease;Scientific Reports;2023-02-15

2. Development and evaluation of physiologically based pharmacokinetic drug-disease models for predicting captopril pharmacokinetics in chronic diseases;Scientific Reports;2021-04-21

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