Gut microbiota metabolizes nabumetone in vitro: Consequences for its bioavailability in vivo in the rodents with altered gut microbiome-Reference-Cited by-同舟云学术

Gut microbiota metabolizes nabumetone in vitro: Consequences for its bioavailability in vivo in the rodents with altered gut microbiome

Published:2019-02-22 Issue:11 Volume:49 Page:1296-1302
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Jourova Lenka¹^ORCID,Anzenbacher Pavel²,Matuskova Zuzana²,Vecera Rostislav²,Strojil Jan²,Kolar Milan³,Nobilis Milan⁴,Hermanova Petra⁵,Hudcovic Tomas⁵,Kozakova Hana⁵,Kverka Miloslav⁶,Anzenbacherova Eva¹

Affiliation:

1. Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic;

2. Department of Pharmacology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech Republic;

3. Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic;

4. Department of Pharmaceutical Chemistry and Drug Control, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Hradec Kralove, Czech Republic;

5. The Czech Academy of Sciences, Institute of Microbiology, Novy Hradek, Czech Republic;

6. The Czech Academy of Sciences, Institute of Microbiology and Institute of Experimental Medicine, Prague, Czech Republic

Funder

Czech Science Foundation

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2018.1558310

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1. Oral drug delivery systems using chemical conjugates or physical complexes