B-Raf inhibitor vemurafenib counteracts sulfur mustard-induced epidermal impairment through MAPK/ERK signaling-Reference-Cited by-同舟云学术

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B-Raf inhibitor vemurafenib counteracts sulfur mustard-induced epidermal impairment through MAPK/ERK signaling

Published:2022-01-05 Issue:2 Volume:46 Page:226-235
ISSN:0148-0545
Container-title:Drug and Chemical Toxicology
language:en
Short-container-title:Drug and Chemical Toxicology

Author:

Xiao Zhiyong¹²,Liu Feng¹²^ORCID,Cheng Junping¹²,Wang Ying¹²,Zhou Wenxia¹²,Zhang Yongxiang¹²

Affiliation:

1. Beijing Institute of Pharmacology & Toxicology, Beijing, China

2. State Key Laboratory of Toxicology and Medical Countermeasures, Beijing, China

Funder

Ministry of Science and Technology of China

Publisher

Informa UK Limited

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/01480545.2021.2021927

Reference37 articles.

1. Arra BioPharma Inc. 2016. Investigator’s brochure encorafenib (LGX818). 8th ed. Bethesda, MD: National Library of Medicine.

2. Poly (ADP-ribose) polymerase (PARP) is essential for sulfur mustard-induced DNA damage repair, but has no role in DNA ligase activation

3. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

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