Germline IGHV3-53-encoded RBD-targeting neutralizing antibodies are commonly present in the antibody repertoires of COVID-19 patients

Author:

Yan Qihong12,He Ping12,Huang Xiaohan12,Luo Kun12,Zhang Yudi12,Yi Haisu3,Wang Qian1,Li Feng4,Hou Ruitian12,Fan Xiaodi5ORCID,Li Pingchao1,Liu Xinglong1,Liang Huan3,Deng Yijun3,Chen Zhaoming1,Chen Yunfei1,Mo Xiaoneng4,Feng Liqiang1,Xiong Xiaoli1,Li Song67,Han Jian6,Qu Linbing1,Niu Xuefeng3,Chen Ling134

Affiliation:

1. Bioland Laboratory, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, People’s Republic of China

2. Savaid Medical School, University of Chinese Academy of Science, Beijing, People’s Republic of China

3. State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China

4. Guangzhou Institute of Infectious Disease, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, People’s Republic of China

5. Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, People’s Republic of China

6. iRepertoire Inc. , Huntsville, AL, USA

7. College of Life Sciences and Chemistry, Hunan University of Technology, Zhuzhou, People’s Republic of China

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences Pilot Strategic Science and Technology Projects

Hunan Urgency Project

Zhongnanshan Medical Foundation of Guangdong Province

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

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