Novel tigecycline resistance mechanisms in Acinetobacter baumannii mediated by mutations in adeS, rpoB and rrf

Author:

Hua Xiaoting123ORCID,He Jintao123,Wang Jingfen123,Zhang Linghong123,Zhang Linyue123,Xu Qingye123,Shi Keren123,Leptihn Sebastian14ORCID,Shi Yue5,Fu Xiaoting67,Zhu Pengfei67,Higgins Paul G.89ORCID,Yu Yunsong123ORCID

Affiliation:

1. Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China

2. Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, People’s Republic of China

3. Regional Medical Center for National Institute of Respiratory Diseases, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China

4. Zhejiang University-University of Edinburgh Institute, Zhejiang University, Haining, People’s Republic of China

5. Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China

6. Single-Cell Center, CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, People’s Republic of China

7. Single-cell Center, Shandong Energy Institute, Qingdao, People’s Republic of China

8. Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany

9. German Centre for Infection Research, Partner site Bonn–Cologne, Cologne, Germany

Funder

National Natural Science Foundation of China

Zhejiang Province Medical Platform

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

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