Synthesis of Stable Isotope Labeled Analogs of the Anti-Hepatitis C Virus Nucleotide Prodrugs PSI-7977 and PSI-352938-Reference-Cited by-同舟云学术

Synthesis of Stable Isotope Labeled Analogs of the Anti-Hepatitis C Virus Nucleotide Prodrugs PSI-7977 and PSI-352938

Published:2011-11 Issue:11 Volume:30 Page:886-896
ISSN:1525-7770
Container-title:Nucleosides, Nucleotides and Nucleic Acids
language:en
Short-container-title:Nucleosides, Nucleotides and Nucleic Acids

Author:

Chun Byoung-Kwon,Du Jinfa,Zhang Hai-Ren,Chang Wonsuk,Ross Bruce S.,Jiang Ying,Bao Donghui,Espiritu Christine L.,Keilman Meg,Steuer Holly M. Micolochick,Furman Phillip A.,Sofia Michael J.

Publisher

Informa UK Limited

Subject

Genetics,Molecular Medicine,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/15257770.2011.614308

Reference11 articles.

1. Discovery of a β-d-2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus

2. PSI-7851, a Pronucleotide of β- d -2′-Deoxy-2′-Fluoro-2′- C -Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication

3. 2′-Deoxy-2′-α-fluoro-2′-β-C-methyl 3′,5′-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: Discovery of PSI-352938

4. Inhibition of Hepatitis C Virus Replicon RNA Synthesis by PSI-352938, a Cyclic Phosphate Prodrug of β- d -2′-Deoxy-2′-α-Fluoro-2′-β- C -Methylguanosine

5. Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

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