Targeting the GLI family of transcription factors for the development of anti-cancer drugs
Author:
Affiliation:
1. Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, United States
Funder
National Institutes of Health/National Cancer Institute
University of Connecticut Office of the Vice President for Research
Publisher
Informa UK Limited
Subject
Drug Discovery
Link
https://www.tandfonline.com/doi/pdf/10.1080/17460441.2021.1832078
Reference115 articles.
1. The GLI gene encodes a nuclear protein which binds specific sequences in the human genome.
2. Hedgehog signaling in animal development: paradigms and principles
3. Role of canonical Hedgehog signaling pathway in liver
4. Context-dependent signal integration by the GLI code: The oncogenic load, pathways, modifiers and implications for cancer therapy
5. Non-consensus GLI binding sites in Hedgehog target gene regulation
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