Synthesis of pyrrolo[2,3-d]pyridazinones as potent, subtype selective PDE4 inhibitors-Reference-Cited by-同舟云学术

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Synthesis of pyrrolo[2,3-d]pyridazinones as potent, subtype selective PDE4 inhibitors

Published:2007-01 Issue:3 Volume:22 Page:309-318
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Giovannoni Maria P.,Cesari Nicoletta,Graziano Alessia,Vergelli Claudia,Biancalani Claudio,Biagini Pierfrancesco,Piaz Vittorio Dal

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/14756360601114700

Reference40 articles.

1. Phosphodiesterase Isozymes

2. PDE4 cAMP-specific phosphodiesterases

3. Phosphodiesterase 4 inhibitors, structurally unrelated to Rolipram, as promising agents for the treatment of asthma and other pathologies

4. Eosinophil Inflammation in Asthma

5. Inhibition of PAF-, LPS-, and cytokine-induced granulocyte accumulation in guinea pig lung by dexamethasone: Evidence that inhibition of IL-5 release is responsible for the selective inhibition of eosinophilia by glucocorticoids in guinea-pigs

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