In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model-Reference-Cited by-同舟云学术

In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model

Published:2019-11-26 Issue:1 Volume:12 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Williams Iwan P.¹^ORCID,Crescioli Silvia¹,Sow Heng Sheng¹²^ORCID,Bax Heather J.¹²,Hobbs Carl³,Ilieva Kristina M.¹⁴,French Elise¹,Pellizzari Giulia¹,Cox Vivienne²,Josephs Debra H.⁵⁶,Spicer James F.⁵⁷,Karagiannis Sophia N.¹^ORCID,Mele Silvia¹^ORCID

Affiliation:

1. St John`s Institute of Dermatology, School of Basic and Medical Biosciences, King`s College London, London, UK

2. IGEM Therapeutics Ltd, London BioScience Innovation Centre, London, UK

3. Wolfson Centre for Age-Related Diseases, King’s College London, London, UK

4. Breast Cancer Now Research Unit, School of Cancer & Pharmaceutical Sciences, King’s College London, Guy’s Cancer Centre, London, UK

5. School of Cancer & Pharmaceutical Sciences, King’s College London, Bermondsey Wing, Guy’s Hospital, Bermondsey Wing, London, UK

6. Department of Medical Oncology, Guy’s and St Thomas’ NHS Foundation Trust, Guy`s Hospital, London, UK

7. Guy’s and St Thomas’ NHS Foundation Trust, Department of Oncology, Guy`s Hospital, Bermondsey Wing, London, UK

Funder

Breast Cancer Now

Cancer Research UK

Medical Research Council

CR UK//NIHR in England/DoH for Scotland, Wales and Northern Ireland Experimental Cancer Medicine Centre

National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) based at Guy's and St Thomas' NHS Foundation Trust and King's College London

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2019.1685349

Reference59 articles.

1. IgE immunotherapy

2. Increased FcγRIIB dominance contributes to the emergence of resistance to therapeutic antibodies in chronic lymphocytic leukaemia patients

3. Half-Lives of Two Types of Rat Homocytotropic Antibodies in Circulation and in the Skin

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