Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope-Reference-Cited by-同舟云学术

Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope

Published:2021-01-01 Issue:1 Volume:13 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Wong Wing Ki¹^ORCID,Robinson Sarah A.¹^ORCID,Bujotzek Alexander²,Georges Guy²^ORCID,Lewis Alan P.³,Shi Jiye⁴^ORCID,Snowden James⁴,Taddese Bruck⁵,Deane Charlotte M.¹^ORCID

Affiliation:

1. Department of Statistics, University of Oxford, Oxford, UK

2. Roche Pharma Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany

3. Data and Computational Sciences, GlaxoSmithKline Research and Development, Stevenage, UK

4. UCB Pharma, Slough, UK

5. Discovery Sciences, BioPharmaceuticals, R&D, AstraZeneca, Cambridge, UK

Funder

Engineering and Physical Sciences Research Council and Medical Research Council

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2021.1873478

Reference34 articles.

1. Local and global anatomy of antibody-protein antigen recognition

2. A convenient method for epitope competition analysis of two monoclonal antibodies for their antigen binding

3. Antibodies Targeting Closely Adjacent or Minimally Overlapping Epitopes Can Displace One Another

4. Epitope Mapping by HDX-MS Elucidates the Surface Coverage of Antigens Associated with High Blocking Efficiency of Antibodies to Birch Pollen Allergen

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