Insulin-like peptide 3 (INSL3) as an indicator of leydig cell insufficiency (LCI) in Middle-aged and older men with hypogonadism: reference range and threshold

Author:

Anand-Ivell Ravinder1,Heng Kee1,Antonio Leen23,Bartfai Gyorgy4,Casanueva Felipe F.5,Maggi Mario6,O’Neill Terence W.7,Punab Margus8,Rastrelli Giulia6,Slowikowska-Hilczer Jolanta9,Tournoy Jos10,Vanderschueren Dirk23,Wu Frederick CW.11,Huhtaniemi Ilpo T.12,Ivell Richard113

Affiliation:

1. School of Biosciences, University of Nottingham, Sutton Bonington, UK

2. Department of Chronic Diseases and Metabolism, Laboratory of Clinical and Experimental Endocrinology, Leuven, KU, Belgium

3. Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium

4. Department of Obstetrics, Gynaecology and Andrology, Albert Szent-Gyorgy Medical University, Szeged, Hungary

5. Department of Medicine, Santiago de Compostela University, Complejo Hospitalario Universitario de Santiago (IDIS), CIBER de Fisiopatología Obesidad y Nutricion (CB06/03), Instituto Salud Carlos III, Santiago de Compostela, Spain

6. Endocrinology and Andrology Unit, “Mario Serio" Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy

7. Centre for Epidemiology Versus Arthritis, The University of Manchester & NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester, UK

8. Andrology Clinic, Tartu University Hospital, and Institute of Clinical Medicine, and Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia

9. Department of Andrology and Reproductive Endocrinology, Medical University of Łódź, Łódź, Poland

10. Department of Geriatrics, University Hospitals Leuven, and Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium

11. Department of Endocrinology, Manchester University NHS Foundation Trust, Manchester, UK

12. Institute of Reproductive and Developmental, Department of Metabolism, Digestion and Reproduction, Imperial College London, Hammersmith Campus, London, UK

13. School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, UK

Publisher

Informa UK Limited

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