Comparison of multiple bioanalytical assay platforms for the quantitation of siRNA therapeutics
Author:
Affiliation:
1. Bioanalysis Discovery & Development Sciences, Janssen Research & Development, LLC, Spring House, PA 19477, USA
2. Translational PK/PD & Investigative Toxicology, Janssen Research & Development, LLC, Spring House, PA 19477, USA
Publisher
Informa UK Limited
Link
https://www.tandfonline.com/doi/pdf/10.1080/17576180.2024.2350266
Reference37 articles.
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2. Clinical Pharmacology of RNA Interference–Based Therapeutics: A Summary Based on Food and Drug Administration–Approved Small Interfering RNAs
3. Infographic: the exciting world of oligonucleotides [Internet]. Abingdon (United Kingdom): Bioanalysis Zone; 2019 Sept 16 [cited 2023 Sept 1]. Available from: http://www.bioanalysis-zone.com/infographic-exciting-world-oligonucleotides_yuduoligo/
4. Oligonucleotide bioanalysis: sensitivity versus specificity
5. Regulated bioanalysis of oligonucleotide therapeutics and biomarkers: qPCR versus chromatographic assays
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